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An open-label pilot study conducted in PD patients showed that oral doses of CBD ranging from 150-400 mg/day, combined with classic antiparkinsonian agents, reduced psychotic...

Besides, several studies have described CBD as a multitarget molecule, acting as an adaptogen and as a modulator, in different ways,...

On the other hand, daily administration of CBD (3 mg/kg) for 14 days decreased both dopamine depletion and tyrosine hydroxylase expression within the striatum of...

sativa and a CB1 and CB2 receptor partial agonist.Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD),...

An open-label pilot study conducted in PD patients showed that oral doses of CBD ranging from 150-400 mg/day, combined with classic...

Despite the consensus among researchers on the potential of CBD as a neuroprotective agent, larger and well-designed randomized clinical...

At low concentrations (sub-micromolar scale), CBD binds to equilibrative nucleoside transporter (ENT), transient receptor potential melastatin type 8 (TRPM8), serotonin 1A receptor...

Moreover, it is not completely understood whether these effects are related to CBD or to other organic compounds present in Cannabis extracts, such as myrcene...

Studies show that CBD can increase AEA concentration by blocking the AEA membrane transporter (AMT) or the FAAH enzyme, which catalyzes AEA hydrolysis.IJMS Free...

Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.Frontiers Phytocannabinoids...